A few things at play here, I think. First, do you see the the little red dot with the question mark in the upper left of the frame in ID? That means the link is missing. ID can't do a proper preview if it can't find the link. Second, ID is color managed. As far as I know, Preview is not. A more accurate check would be against the image in Photoshop. Third, you've got a drop shadow. I suspect the Image is RGB and the transparency blend space is set to CMYK. Fourth, you are, indeed, looking at a compressed preview, not the actual pixels. The quality of the preview depends on the settings (display quality) and the size/resolution ratio at which the image was saved.
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