The optimizeer lets you do a number of things, including trowing away data that may not be obvioulsly apparent and may not hurt the usability of the file if it disappears. It also allows you to do a "usage audit" that will tell you just exactly what is taking up the space. If it's images, and they're already at marginal resolution, you may never get to what you need. Not all files can reach a small target.
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